Dementia is the umbrella term used
to describe a multitude of conditions that exhibit memory loss and confusion. There are dozens
of causes of dementia aside from Alzheimer’s. Sometimes it’s hard to
distinguish dementia from what’s know as delirium, or severe confusion due to illness. Delirium is reversible and may be caused by dehydration,
pneumonia, drug reactions, or a severe exacerbation of many pre-existing
conditions. Rarely are personality changes found to be due to brain tumors.
Dementia can also be caused by
hypo-thyroidism, normal pressure hydro-cephalus (NPH,) and vitamin
deficiencies. These conditions are treatable and the dementia may be reversed
or at least greatly relieved.
Alzheimer’s Disease - Most common
type of dementia; accounts for an estimated 60 - 80 percent of cases.
* Difficulty remembering names and recent events
is often an early clinical symptom; apathy and depression are also often early
symptoms. Later symptoms include impaired judgment, disorientation, confusion,
behavior changes and difficulty speaking, swallowing and walking.
Vascular Dementia - also known as
multi-infarct or post-stroke dementia or vascular cognitive impairment)
Considered the second most common
type of dementia.
* Impairment is caused by decreased blood flow
to parts of the brain, often due to a series of small strokes that block
arteries.
* Symptoms often overlap with those of
Alzheimer’s, although memory may not be as seriously affected.
Multi-infarct dementia is caused by
repeated strokes sometimes mini-strokes or Transient Ischaemic Attacks (TIA,)
but it also may occur if several larger strokes have happened.
Mixed Dementia - Characterized by
the hallmark abnormalities of Alzheimer’s and another type of dementia - most
commonly vascular dementia, but also other types, such as dementia with Lewy
bodies.
* Recent studies suggest that mixed dementia is
more common than previously thought.
Lewy Body Disease (LBD) - Pattern
of decline may be similar to Alzheimer’s, including problems with memory and
judgment as well as changes in behavior. Alertness and severity of cognitive
symptoms may fluctuate daily. Visual hallucinations, muscle rigidity and
tremors are common. LBD is closely related to Parkinson’s disease and may
co-exist with that. Rigidity and difficulty initiating movement along with
severe hallucinations, delusions and aggressive outbursts usually show up
before real memory loss is apparent. It’s quite difficult to distinguish from
Alzheimer’s and may benefit from some of the same therapy.
Parkinson’s Disease - Many people
who have Parkinson’s disease (a disorder that usually involves movement
problems) also develop dementia in the later stages of the disease. The
hallmark abnormality is Lewy bodies (abnormal deposits of the protein alphasynuclein)
that form inside nerve cells in the brain.
Frontotemporal Dementia (FTD) -
Involves damage to brain cells, especially in the front and side regions of the
brain. The frontal lobe governs mood, behavior, and self-control.Damage leads to changes in the way a
person feels and expresses emotion, and loss of judgment. Typical symptoms
include changes in personality and behavior and difficulty with language. No
distinguishing microscopic abnormality is linked to all cases.
* Pick’s disease, characterized by Pick’s
bodies, is one type of frontotemporal dementia.
Creutzfeldt-Jakob Disease (“Mad Cow”) -
Rapidly fatal disorder that impairs memory and coordination and causes
behavior changes. Variant Creutzfeldt-Jakob disease is believed to be caused by
consumption of products from cattle affected by mad cow disease. Caused by the
misfolding of prion protein throughout the brain.
Normal Pressure Hydrocephalus (NPH)
- Caused by the buildup of fluid in
the brain. Symptoms include difficulty walking, memory loss and inability to
control urination. Can sometimes be corrected with surgical installation of a
shunt in the brain to drain excess fluid.